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In parallel, the kynurenine/tryptophan ratio was increased in symptomatic TTR-V30M carriers, supporting inflammatory activation in manifest disease

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This might include starting with switching to a low-residue diet, and using split-dose, low-volume prep with additional osmotic agents such as Magnesium Citrate [4]

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When stored inside ferritin, the ferrous iron that was transported into the cell is oxidized back to the ferric state